HIV
Human immunodeficiency virus
Example
I didn't realize how rampant HIV was in Africa
HIV definition by Slang.net - The Slang Dictionary
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HIV means human immunodeficiency virus, which is a deadly disease that attacks the human immune system. It commonly appears with the AIDS acronym.
HIV is transmitted primarily through unprotected sex, hypodermic needles, contaminated blood transfusions, birth from mother to child, and breastfeeding. By weakening the immune system, dangerous cancers and infections can more easily attack a person and wreak havoc.