In my humble and respectful opinion
IMHARO, I think you should change the oil in your car every 3 months even if you don't drive that much.
|IMHO||In my humble opinion|
|IMHO||In my honest opinion|
|IMAO||In my arrogant opinion|
|IMBO||In my biased opinion|
|IMCO||In my considered opinion|
IMHARO is an expanded form of the more common IMHO. Someone who begins or ends a message with IMHARO wants you to know that the opinion they've expressed is not only humble but respectful.
As such, you should feel free to disagree with someone who pairs their opinion with IMHARO. After all, if the person who sent you IMHARO is truly humble and respectful, they'll understand that their opinion may be wrong.