Sis
Sister
Example
Hey sis, can you pick me up after school 2morrow?
sis definition by Slang.net
This page explains what the abbreviation "sis" means. The definition, example, and related terms listed above have been written and compiled by the Slang.net team.
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A common, playful abbreviation used for sister.
The abbreviation may be used to refer to a biological sister or your bestie. The term is similar to the bro abbreviation.