WTFO
WTFO definition by Slang.net
This page explains what the acronym "WTFO" means. The definition, example, and related terms listed above have been written and compiled by the Slang.net team.
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WTFO is an expression of astonishment, which you're most likely to encounter during a text or chat conversation. It means roughly the same thing as "What in the world?" or "How the heck?"
The O in WTFO stands for "over." In radio communications, ending a message with "over" tells the recipient that you're waiting for a reply. In this case, the person who sent you WTFO is likely hoping you'll explain the message that prompted them to send you this crass acronym.